Proin a prevalent veterinary type of phenylpropanolamine (PPA), is a sympathomimetic used to treat mutts with incontinence. Beside this, phenylpropanolamine can likewise alleviate stuffy noses which is the reason it’s occasionally utilized as a part of nasal decongestant showers.

The medication works by invigorating alpha-adrenergic and beta-adrenergic receptors in a puppy’s body prompting the arrival of norepinephrine, which thus enhances the urethral conclusion weight.

Is It Safe?

A few owners are worried about the danger of stroke, however this is by all accounts uncommon, especially in solid mutts. Strokes taking after the utilization of phenylpropanolamine are presumably connected to the bring up in circulatory strain the medication can bring about, which would put pooches with coronary illness or hypertension at the most hazard. We prescribe addressing the vet about this in the event that it stresses you.

Beside a conceivable increment in the danger of stroke, there are a few mutts who must be checked precisely amid treatment. This incorporates those with the accompanying medicinal conditions:

  • Diabetes mellitus
  • Glaucoma
  • Coronary illness
  • Hypertension
  • Hyperthyroidism
  • Prostate extension

There are additionally a few medications which could interface with phenylpropanolamine including MAOIs (e.g. Quieting Collar), NSAIDs, other sympathomimetic medications and a few antidepressants. It ought not to be given to puppies before they get a vaporous sedative.

Pregnancy: It has all the earmarks of being safe for use amid pregnancy, yet may prompt diminished ovum implantation.

Safety Guidelines

We prescribe the accompanying rules to utilize this medication securely:

  • Try not to use without veterinary approval
  • Talk about the stroke hazard with your vet in the event that you are concerned
  • Inform the vet of any therapeutic conditions your canine endures with
  • Find a way to decrease the heaviness of your canine on the off chance that they are overweight
  • Inform the vet of whatever other solutions or supplements you are providing for your canine
  • Give a lot of water amid treatment

What Is It Used For?

Proin is only utilized for the treatment of incontinence, however may likewise be powerful in the treatment of retrograde discharge.


Here are a portion of the reactions your puppy may encounter amid treatment with phenylpropanolamine:

More Common:

  • Anxiety
  • Restlessness
  • Decreased appetite
  • Increased blood pressure
  • Increased heart rate
  • Increased thirst
  • Lethargy
  • Urinary retention
  • Vomiting
  • Weight loss

Less Common:

  • Allergic reaction
  • Stroke

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