Phenobarbital is a barbiturate used to forestall seizures or control status epilepticus (seizures going on for 30 minutes or more). Since it is moderately shabby and is powerful for the dominant part of puppies, it’s a typical decision of solution. It is additionally utilized less regularly for its calming properties.

Phenobarbital versus potassium bromide: When it comes to treating pets with seizures, the other go-to medication is bromide. Bromide is a decent decision for youthful pooches or puppies with debilitated liver capacity, however we prescribe phenobarbital at whatever point conceivable in light of the fact that it has a tendency to be more viable. You can likewise utilize the two solutions together if it is possible that one all alone does not function admirably enough.

Is It Safe?

Phenobarbital is very safe for healthy canines however can put some strain on the liver, making it unsatisfactory for those with poor liver capacity unless defensive medications are given in conjunction. Utilize carefully while treating those with the accompanying conditions:

  • Adrenal insufficiency
  • Anemia
  • Heart or respiratory disease
  • Hypovolemia

he injectable structure ought to be regulated gradually to maintain a strategic distance from respiratory melancholy, and ought to never be infused perivascularly or subcutaneously.

Pregnancy: This solution can harm amid pregnancy and ought not be utilized as a part of these cases unless totally fundamental.

Use Guidelines

The accompanying rules will help you securely treat your pooch with phenobarbital:

Only begin treatment under the guidance and approval of a vet

  • Tell the vet about any medical conditions your dog has, or any other medicines/supplements you are giving him
  • Avoid injecting subcutaneously or perivascularly
  • The medicine should not be injected at a rate of more than 60 mg per minute
  • Administer the drug at roughly the same time every day to keep levels stable
  • When used long-term, regularly blood testing (often every 6 months) is advised
  • Contact the vet if treatment does not reduce seizure activity

An expansive number of medications connect with phenobarbital, so dependably enlighten your vet concerning whatever other pharmaceuticals (or even supplements) your canine is taking. A portion of the more regular medications which connect with phenobarbital incorporates antihistamines, MAOIs, corticosteroids and anti-infection agents, for example, doxycycline and metronidazole.

What Is It Used For?

This solution is generally used to treat the accompanying conditions:

  • Compulsive behaviors
  • Seizures

It is likewise infrequently utilized as a narcotic, or in uncommon cases, for the treatment of urgent practices.


The medication is regularly very much endured. Be that as it may, amid treatment the accompanying unfriendly impacts could happen:


  • Anxiety
  • Increased frequency of urination
  • Increased hunger
  • Increased thirst
  • Lethargy
  • Loss of coordination


  • Anemia
  • Liver damage
  • Reduced neutrophil count
  • Reduced platelet count
  • Superficial necrolytic dermatitis (SND)

Expanded thirst, expanded longing, expanded pee, sedation and loss of coordination get to be normal when blood serum levels of the medication are high. Manifestations of tension and torpidity tend to take a break, yet tell your vet in the event that they don’t.

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